Open access
Aug 2026
Pdcd4–Rictor interaction suppresses mTORC2-PFKFB3 axis and tumorigenesis in NSCLC
It is found that Pdcd4 suppresses tumorigenesis through disrupting mTORC2 complex formation by binding with the rapamycin-insensitive companion of mTOR (Rictor), a core component of the mTORC2 complex.
Qing Wang, Yu Xin, Elham Zokaei et al.
· Neoplasia · 0 citations