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Libbie M. Silverman

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Open access Oct 2026

Metastatic Bone Disease Is Associated With Longitudinal Muscle Loss and Reduced Survival in Kidney Cancer

ABSTRACT Background Cachexia is a multifactorial muscle wasting syndrome and is responsible for 20%–40% of cancer‐related deaths, yet no FDA‐approved therapies exist. Preclinical studies suggest that metastatic bone disease may contribute to muscle wasting, but this relationship has not been evaluated in clinical popul...

Jon-Luc Poirier, S. T. Jines, Libbie M. Silverman et al. · 0 citations

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