Open access
Jul 2026
A synthetic virus-like assembly unlocks dual-antigen presentation for broad-spectrum anti-SARS-CoV-2 immunity
This characterized virion-mimetic structural vaccine not only induces the production of high-efficiency antibodies against both the spike and N proteins but also elicits robust S1-specific and N-specific CTL responses in animal models, creating an optimal microenvironment for eliciting potent and broad-spectrum adaptive immune responses.
Jingjing Zhang, Fen Zeng, Yanmei Li et al.
· Scientific Reports · 0 citations