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Open access Aug 2026

Comparison of a Novel Intracorporeal Anastomosis Versus Extracorporeal Anastomosis for Colon Cancer: A Propensity Score-Weighted, Prospective Idea, Development, Exploration, Assessment, Long-term Stage 2b Cohort Study.

BACKGROUND Intracorporeal anastomosis benefits are often offset by high costs and technical complexity. OBJECTIVE To evaluate the safety, efficacy, and cost-neutrality of a novel U-tied functional end-to-end anastomosis v. conventional laparoscopic-assisted colectomy. DESIGN Prospective cohort study following the I...

Qiang Du, Tian Wei, Li-Bin Huang et al. · 0 citations
Open access Sep 2026

Integrative Multi‐Omics Profiling Reveals Age‐Associated Genomic and Tumor Microenvironmental Heterogeneity in Colorectal Cancer

Early‐onset colorectal cancer (EOCRC) is increasing worldwide, yet the molecular basis underlying its age‐related heterogeneity remains insufficiently defined. To address this gap, we performed whole‐exome sequencing in a Chinese EOCRC cohort diagnosed before 40 years of age ( n  = 111), bulk transcriptome sequen...

Yang Guo, Ya-Jiao He, Tao Zhou et al. · 0 citations

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