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Author

Lijing Zhan

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Open access Aug 2026

Cancer Cell Line Heterogeneity Imposes a Primary Bottleneck for Virtual Perturbation Screening at Scale

UniPert-G2CP (Li et al., Cell, 2026) bridges genetic and chemical screens from molecular representation to phenotype modeling across five cancer cell lines [1]. Here we extend this architecture to 162 cell lines, 32,039 compounds, and genome-wide output (12,328 genes), and find that the resulting prediction platform re...

Kai-Qi Wei, Lijing Zhan, Can-Yang Qi · 0 citations

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