Open access
Jul 2026
Targeting nuclear export and Janus Kinase/Signal Transducer and Activator of Transcription (JAK/STAT) signalling in myelofibrosis: A novel combinatorial strategy that impacts intrinsic and microenvironment‐related pathways
It is highlighted that selinexor plus ruxolitinib affects both MF haematopoietic cell–intrinsic and microenvironment‐related pathways, providing a novel disease‐modifying strategy with the potential to improve clinical outcomes in patients with MF.
T. Kashyap, Andrea A. Ellero, C. Walker et al.
· British Journal of Haematolo... · 0 citations