Open access
Sep 2026
19 Dissecting ARNT Expression Patterns in RCC and Association with Outcomes
Abstract Background Hypoxia signaling is a key driver of renal cell carcinoma (RCC) and is mediated by HIF-dependent transcription. ARNT (HIF-1β) is an essential HIF binding partner, but its expression and clinical relevance in RCC are poorly defined. With ARNT inhibitors in development, characterizing ARNT expression...
Yu-Wei Chen, S. Nazari, A. Elliott et al.
· The Oncologist · 0 citations