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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Liliana Tchernev

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Open access Aug 2026

Spatial remodeling of the thymic stroma with age disrupts niches for T cell selection and tolerance

A spatially resolved multi-omic atlas of the aging mouse thymus is generated and reframe thymic involution as spatial stromal reorganization that links stromal remodeling to impaired thymopoiesis, central tolerance, and immune aging.

Andreas Tarcevski, Fatima Dhalla, Joshua W. Moore et al. · 0 citations

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