Author

Lin Chen

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Open access Sep 2026

An injectable ROS-responsive PRP-loaded hydrogel attenuates osteoarthritis by reducing oxidative stress, inflammation and chondrocyte apoptosis.

Osteoarthritis (OA) is a degenerative joint disease mainly characterized by oxidative stress, inflammatory responses, and loss of cartilage matrix. Although platelet-rich plasma (PRP) has been applied in OA treatment, its intra-articular use is still limited by insufficient local retention and short duration of action....

Ming-Deng Xu, Xu Deng, Shuai-Jun Hu et al. · Biomaterials Advances · 0 citations

Open access Sep 2026

Titanium-Coated Implants With Advanced Antioxidant Properties Are Used in the Design and Development of a Regenerative Repair Strategy for Reversing Senile Osteoporosis.

Senile osteoporosis (SOP) creates a hostile peri-implant microenvironment characterized by impaired osteogenesis, excessive bone resorption, and persistent oxidative stress, leading to poor osseointegration. Here, we developed a dual-functional titanium surface (Ti-Ta@RS) co-modified with a thioctic acid derivative and...

Shuai-Jun Hu, Ao Zhou, Lin Chen et al. · Advanced Healthcare Material... · 0 citations