Lin-Cheng Yang

Novel acylation modifications in cerebrovascular disease: Molecular mechanisms, crosstalk and therapeutic potential.

Secondary injury in cerebrovascular disease involves energy failure, oxidative stress, neuroinflammation, blood-brain barrier disruption and neurovascular unit dysfunction. Novel lysine acylations, including lactylation, succinylation, beta-hydroxybutyrylation and crotonylation, have emerged as interfaces through which...