Lin-Fei Li

A cfDNA fragmentomics classifier for noninvasive differentiation of benign and malignant renal masses

Noninvasive differentiation of malignant and benign renal masses remains a major clinical challenge, particularly for radiologically indeterminate lesions. Here, we developed and validated a plasma cell-free DNA (cfDNA) fragmentomics-based machine learning classifier for renal mass characterization. The model was train...