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Sep 2026

Panaxytriol up-regulates CYP2B6 expression through PXR and CAR and their interactions with RXRα and SRC-1.

ETHNOPHARMACOLOGICAL RELEVANCE Cytochrome P450 2B6 (CYP2B6) is a critical drug-metabolizing enzyme, and its expression is regulated by the nuclear receptors. Panaxytriol (PXT), a prominent bioactive constituent extracted from the roots of Panax ginseng C.A. Meyer, was found to induce cytochrome P450 3A4 (CYP3A4) via pr...

Lin Huang, Yin-Yue Du, Qi Gu et al. · 0 citations
Open access Sep 2026

Chemistry-informed Bayesian control and policy distillation for autonomous pH adjustment in diverse chemical systems

Adjusting pH of an arbitrary solution to a specified target remains difficult to automate when buffering behavior is unknown, nonlinear, and composition-dependent. We formulate pH adjustment as a sequential inference-and-control problem and develop a chemistry-informed Particle Filtering (PF) Bayesian controller that u...

Si-Yuan Zhang, Lin Huang, Tian-Ci Shi et al. · 0 citations

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