Review
Open access
Sep 2026
Metabolic reprogramming-mediated therapeutic resistance in renal cell carcinoma: Mechanisms and targeted intervention strategies
Summary Renal cell carcinoma (RCC) is one of the most frequent urological tumors and exhibits metabolic reprogramming alongside genetic mutations. RCC cells reprogram pathways involved in glucose, lipid, and amino acid metabolism to meet their energy and anabolic demands. In recent years, targeted drugs, immunotherapy,...
Han Wu, Xin-Xin Gan, Si-Yi Wang et al.
· iScience · 0 citations