Open access
Oct 2026
A Dual‐Delivery System Designed to Overcome EV‐Mediated Ferroptosis Resistance for Efficient Solid Tumor Therapy
ABSTRACT Tumor‐derived extracellular vesicles (EVs) are emerging as critical mediators of metabolic adaptation, yet their role in orchestrating ferroptosis resistance within the tumor microenvironment remains poorly understood. Here, we show that highly malignant osteosarcoma (OS) cells respond to ferroptotic stress by...
Ye-Chao Shen, Zhen-Guo Cao, Ze-Nan Wang et al.
· Advancement of science · 0 citations