Finerenone Ameliorated Ventricular Remodeling Post Myocardial Infarction in Rats by Reducing NF-KB Pathway-mediated Pyroptosis.
Myocardial infarction (MI) remains a leading cardiovascular cause of mortality in patients, primarily driven by adverse post-MI ventricular remodeling tightly linked to inflammation. Finerenone, the first non-steroidal mineralocorticoid receptor (MR) antagonist, is clinically indicated to improve cardiovascular and ren...