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Author

Linlin Zhao

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2 papers indexed here

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Clinical trial Open access Sep 2026

Effects of Intranasal Dexmedetomidine on the Night Before Surgery on Postoperative Delirium in Elderly Patients Undergoing Total Knee/Hip Arthroplasty. A Parallel-Arm, Randomized Controlled, Non-Inferiority Trial

Importance It is crucial to identify preoperative treatment methods that can safely and effectively reduce the incidence of postoperative delirium. Objective To evaluate whether preoperative intranasal dexmedetomidine administration for preventing postoperative delirium is non-inferior to intravenous dexmedetomidine in...

Yang-Yang Chen, Ke-Qin Wang, Yu-Qi Zhang et al. · 1 citation
Open access Aug 2026

Effect of Intranasal Dexmedetomidine on the Night Before Surgery for Postoperative Delirium in Older Patients Undergoing Total Hip or Knee Arthroplasty: A Randomized Clinical Trial

Importance Postoperative delirium is a common and serious neurocognitive complication in elderly arthroplasty patients, with preoperative poor sleep as a key risk factor. Effective preoperative prevention strategies remain an urgent clinical need. Objective To assess preoperative intranasal dexmedetomidine for preventi...

Yu-Cheng Liu, Ke-Qin Wang, Yu-Qi Zhang et al. · 1 citation

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