Review
Open access
2026
Tumor Microenvironment-Mediated Resistance in HER2-Positive Breast Cancer: Recent Advances and Therapeutic Challenges
: Human epidermal growth factor receptor 2 (HER2)-positive breast cancer is associated with aggressive disease and poor prognosis. Despite advances in HER2-targeted therapies, resistance remains a major clinical challenge. This review focuses on the mechanisms of resistance to HER2-targeted therapies, with particular e...
Yu-Tong Zhang, Xuan-Yi Lv, Zhi-Hong Deng et al.
· Oncology Research · 0 citations