Molecular Profiles, Treatment-Associated Survival, and Prognosis in Early-Onset Versus Late-Onset Gastric Cancer: A Systematic Review and Meta-Analysis
Background: Whether early-onset gastric cancer (EOGC) represents a distinct clinical entity requiring age-specific management remains uncertain. We synthesized molecular profiles, treatment-associated survival, and prognosis to determine what current evidence supports in practice and requires prospective validation. Me...