Basal Ganglia Perivascular Space Enlargement Is Associated with Sustained Amyloid-β Accumulation in the Alzheimer's Disease Continuum: A Longitudinal Study.
RATIONALE AND OBJECTIVES The perivascular spaces (PVS) serve as primary conduits for brain waste clearance. PVS enlargement (EPVS) is commonly observed in aging and neurodegenerative conditions. However, it remains unclear whether EPVS influences the β-amyloid (Aβ) deposition in Alzheimer's disease (AD). MATERIALS AN...