Author

Lin Zhou

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Open access Aug 2026

LDH-mediated autophagic full-chain blockade for Multiple Myeloma treatment by targeting circ_0008255/miR-192-5p/ATG2A axis

This study identifies an autophagy-associated circRNA, circ_0008255, which is markedly upregulated in MM patients and closely correlated with poor disease prognosis, offering a promising therapeutic paradigm for MM.

Zhenhua Wang, He-Fei Ren, Kun Wang et al. · Bioactive Materials · 0 citations

Open access Aug 2026

Integrating single-cell analysis and machine learning algorithms to explore lactylation-related molecular mechanisms and therapeutic responses in clear cell renal cell carcinoma and identifying CDT1 as a potential biomarker

This study delineates the molecular heterogeneity associated with lactylation-related gene expression in ccRCC and presents a validated prognostic model that identifies CDT1 as a novel oncogene and potential biomarker, providing insights into metabolic–epigenetic crosstalk and a foundation for future therapeutic develo...

Yue Zhang, Hang Zhou, Bihui Zhang et al. · Frontiers in Endocrinology · 0 citations