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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Linfeng Guo

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Review Open access Aug 2026

The mechano-immunological barrier in fibrosis-associated lung cancer: targeting matrix stiffness and the Piezo1 axis for microenvironment normalization

While mechanotransduction influences various lung cancer subtypes, this review focuses specifically on fibrosis-associated non-small cell lung cancer (NSCLC), where the progression from pulmonary fibrosis to malignancy is mediated by aberrant mechanotransduction. Progressive extracellular matrix (ECM) stiffening (8–25...

Linfeng Guo, Jia Wang, Bao-Yi Ni et al. · 1 citation · ⚡1

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