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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Ling Hou

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Review Open access Sep 2026

Immune ontogeny in childhood-onset systemic lupus erythematosus: effect of immune maturity on disease phenotype and therapeutic responses

Childhood-onset systemic lupus erythematosus (cSLE) occurs during a period of significant developmental changes in the immune system, when tolerance checkpoints and regulatory networks continue to mature. Compared with adult-onset SLE (aSLE), cSLE more frequently presents with strong type I interferon activity, BAFF-in...

Wan-Feng Xu, Qing-Feng Sun, Mei-Hui Li et al. · 0 citations

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