Aug 2026
KLK6 is Associated with a Neutrophil-Dominant Immunosuppressive Microenvironment and Epigenetic Deregulation in Lung Adenocarcinoma.
Findings suggest that KLK6 overexpression in LUAD is driven in part by promoter hypomethylation and is closely linked to a neutrophil-dominant immunosuppressive microenvironment and may serve as a promising prognostic biomarker and a potential therapeutic target for LUAD.
Ling-Jie Chen, Wen-Bo Zhou, Jiong-Jie Wang et al.
· Current Medicinal Chemistry · 0 citations