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Ling-Ling Li

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Review Open access Sep 2026

Polydatin Delivery Systems and Nanomedicine: Pharmacology, Preclinical Evidence, and Translation

Background: Polydatin has shown anti-inflammatory, antioxidant, and cytoprotective effects in preclinical studies. Its development is limited by low oral bioavailability, extensive metabolism, and poorly defined tissue exposure. Objectives: This review summarizes the pharmacology and delivery systems of polydatin, dist...

Xiao-Ya Li, Ling-Ling Li, Yong-Fang Yuan et al. · 0 citations
Open access Aug 2026

Polydatin in combination with hawthorn flavonoids alleviates atherosclerosis by inhibiting mitochondrial division through the YTHDF2-DRP1 axis.

INTRODUCTION The combination of polydatin and hawthorn flavonoids (PH), a traditional Chinese medicine formulation for activating blood circulation and detoxification, has shown the potential to counteract atherosclerosis, but the mechanisms underlying its effects remain unclear. PURPOSE To investigate the protective...

Yu-Juan Li, Xiao-Nan Zhang, Sheng-Jie Yang et al. · 1 citation

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