Open access
Aug 2026
DUSP1 Inhibits Mechanotransduction and MAPK Signalling to Alleviate Myocardial Cell Hypertrophy.
The findings identify a previously underappreciated role of DUSP1 in linking mechanical stress-induced signalling with MAPK activation and pathological cardiac remodelling, suggesting DUSP1 restoration as a potential therapeutic strategy for HCM-like cardiac remodelling.
Xiaoyuqian Zhong, Ling-Ran Kong, You-Jun Zhang et al.
· Clinical and Experimental Ph... · 0 citations