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FABPs-mediated lipid signaling pathways in tumor reprogramming: bidirectional crosstalk with the immune microenvironment.
Fatty acid-binding proteins (FABPs) are cytoplasmic lipid chaperones that regulate intracellular fatty acid trafficking and metabolic homeostasis. Increasing evidence identifies FABPs as key drivers of tumor metabolic reprogramming. Within the broader tumor microenvironment (TME), particularly its immune compartment, t...