Author

Lingling Guo

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Sep 2026

Broad‐Spectrum Recombinant Antibody Profiled by Hapten Prediction and Its Application in Immunoassay for Anabolic‐Androgenic Steroids

Illegal use of anabolic‐androgenic steroids (AASs) to feed livestock can lead to food residues and endanger public health. Thus, the development of rapid, sensitive detection methods for AASs is urgently needed for AASs to safeguard food safety. In this study, four novel haptens were designed for six AASs (androstenedi...

Jia-Lin Hu, Xin-Xin Xu, Mao-Zhong Sun et al. · Small Methods · 0 citations

Aug 2026

On-site detection of an emerging fungicide: developing an immunochromatographic assay for thifluzamide through de novo hapten design and synthesis.

Thifluzamide (THF), a novel succinate dehydrogenase inhibitor fungicide, is widely used to control crop diseases; however, excessive residues pose potential risks to human health. To guide hapten design, a detailed analysis of the spatial structures and electrostatic potential distributions of THF and its haptens was c...

Xu-Yang Ma, Aihong Wu, Ling-Ling Guo et al. · Food Chemistry · 0 citations

Sep 2026

A Dual-T-Line Immunochromatographic Assay Based on Computational Chemistry-Guided Hapten Design for Rapid On-Site Detection of Chloroneb in Agricultural and Environmental Samples

The health risks posed by chloroneb (CHL), a representative fungicide, in agricultural products and the environment necessitate rapid detection methods. Here, computational chemistry-aided rational hapten design yielded a high-performance monoclonal antibody against CHL (IC50 = 2.63 ng/mL), guided by analysis of its...

Feng He, Ling-Ling Guo, Mao-Zhong Sun et al. · Journal of Agricultural and... · 0 citations