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Author

Lingshu Wang

3 papers indexed here

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Open access Jul 2026

Fusion Peptide Priming and Trimer Boosting Strategies for HIV Vaccine Development in Guinea Pigs 2308606

The case for FP priming as a powerful method for engaging a vulnerable HIV Env epitope is strengthened, demonstrating that the TTT platform may serve as an effective boost to epitopes beyond FP, and how trimer architecture and dosing influence the trajectory of epitope targeting is clarified.

Shreyanshu Ray, Cheng Cheng, K. McKee et al. · 0 citations
Open access Aug 2026

Potent type-specific de novo antibodies complement broadly reactive imprinted antibodies in immune responses to SARS-CoV-2 variants

Hundreds of recall and de novo neutralizing monoclonal antibodies are isolated and characterized after sequential exposures to SARS-CoV-2 variants in ancestral-imprinted humans to reveal the distinct contributions of recall and de novo antibodies to a balanced immune response and underscore the benefit of updated boost...

T. Johnston, Shuk-Hang Li, M. Painter et al. · 2 citations
Aug 2026

Full-length premembrane protein is not required for mature Zika virus particle assembly.

Assembly of flaviviruses such as Zika virus (ZIKV), dengue virus, and West Nile virus in the host cell endoplasmic reticulum is driven by the structural envelope (E) and premembrane (prM) proteins. The formation of an infectious virion requires cleavage of prM by the host furin protease during a maturation step that is...

Kimberly A. Dowd, Michelle Schroeder, Egan Sanchez et al. · 0 citations

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