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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Linhong Jin

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Open access Oct 2026

Design, synthesis, and evaluation of antifungal and antibacterial activities of novel quinazolinone-formononetin derivatives.

BACKGROUND Plant pathogenic fungi and bacteria cause substantial losses in agricultural production worldwide, and escalating resistance to conventional agrochemicals necessitates the development of novel, environmentally benign pesticides. Formononetin, a naturally occurring isoflavone, exhibits promising bioactivities...

Xiao-Yan Pan, Jun-Rong Song, Qing-Xue Hu et al. · 0 citations
Aug 2026

Design, Synthesis, and Antifungal Activity of Novel Oxadiazole-Pyrazole-Triazole Derivatives: Insights into Cellular Disruption Revealed by Integrated Transcriptomic and Proteomic Analyses.

Mechanistic investigations revealed that L22 induces severe cellular disruption, characterized by compromised membrane integrity, cell wall deformation, and broad dysregulation of sterol/lipid metabolism, carbohydrate utilization, mitochondrial respiration, and stress-response pathways, warranting further development f...

Fa-li Wang, Xiao-li Ren, Lin Gao et al. · 0 citations
Jul 2026

Design, Synthesis, and Antifungal Activity of Thiazolidinedione Derivatives Incorporating Thioamide and Piperidine Moieties.

A series of thiazolidinedione derivatives containing thioamide and piperidine moieties were designed, synthesized, and evaluated for antifungal activity against plant pathogenic fungi. Several compounds exhibited potent antifungal activity, among which Z17 was the most active against Rhizoctonia solani (EC50 = 1.8 μg/m...

Junrong Song, Shuang Feng, Miaohe Zhang et al. · 0 citations
Aug 2026

Novel Flavonol Derivatives Bearing a 1,2,3,4-Tetrahydroquinoline Moiety: Design, Synthesis, and Anti-Phytophthora capsici Activity.

Mechanistic studies revealed that Q8 disrupted cell membrane integrity and inhibited succinate dehydrogenase (SDH) activity, with computational simulations suggesting a higher binding affinity for SDH than fluopyram.

Qing-Xue Hu, Xiao-Ting Geng, Fang Tian et al. · 0 citations

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