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Lino Riepenhausen

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Open access Aug 2026

Large-scale structure prediction of DUF-containing protein-protein interactions

Whether AlphaFold 3 complex prediction, combined with STRING evidence and domain-level analysis of interfaces and interaction partners, can help identify and characterize DUF-containing proteins and suggest roles for DUF4130 in nucleic-acid-associated radical-SAM biology and DUF5819 in a bacterial system related to vitamin-K-dependent carboxylation are suggested.

Lino Riepenhausen, Francesco Costa, Antonina Andreeva et al. · bioRxiv · 0 citations