AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
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Gut microbiome dysbiosis is associated with aldosterone overproduction in idiopathic hyperaldosteronism
Summary Idiopathic hyperaldosteronism (IHA) is a significant cause of secondary hypertension. Emerging evidence links the gut microbiota to endocrine and cardiovascular diseases. We integrated human genetics, multi-omics, and fecal microbiota transplantation (FMT) to investigate the association between IHA and gut micr...
Proteomic profiling reveals novel insights into hypercortisolism adrenal adenomas.
Comprehensive proteomic profiling of adrenal cortisol-producing adenomas reveals a central role for cholesterol metabolic reprogramming in the pathogenesis of CPAs and downregulation of calcium binding protein 39 like (CAB39L) is uncovered as a key driver of pathological cortisol production.