Open access
Aug 2026
FOXO4 enhances high glucose-induced HK-2 cell damage and inflammation by targeting TFPI2 in diabetic nephropathy.
FOXO4 promotes HG-induced HK-2 cell damage and inflammation via regulating TFPI2 in vitro and alleviates renal injury and inflammation in vivo, and TFPI2 knockdown alone alleviates renal injury and inflammation in vivo.
Liqin Mu, Yu Zhao, Yang Li et al.
· Kidney Research and Clinical... · 0 citations