Author

Liu-Qin Zhao

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Open access Aug 2026

Multi-omics analysis identifies fibroblast IGFBP5 as a key target of anti-TNFα therapy in ulcerative colitis

Background Resistance to anti-TNFα therapy (e.g., infliximab) in ulcerative colitis (UC) remains a significant clinical challenge, with the underlying cellular and spatial mechanisms poorly understood. Methods We integrated bulk transcriptomics, single-cell RNA sequencing (scRNA-seq), and spatial transcriptomics (ST) f...

Pei-Hong Li, Yi-Kun Zhang, Liu-Qin Zhao et al. · Frontiers in Immunology · 0 citations

Sep 2026

(S)-SA, a bioactive flavonoid from Dalbergiae Odoriferae Lignum, alleviates cerebral ischemia-reperfusion injury via SLC11A2-mediated ferroptosis inhibition.

BACKGROUND Cerebral ischemia-reperfusion injury (CIRI) remains a major barrier to neurological recovery after ischemic stroke, and effective pharmacological interventions targeting upstream neurovascular unit mechanisms related to ferroptosis and blood-brain barrier (BBB) injury are limited. PURPOSE This study aimed...

Jiang-Ming Zhu, Ju Ye, Liu-Qin Zhao et al. · Phytomedicine · 0 citations