Sep 2026
Palmitoylethanolamine alleviates osteoclast activation and reduces bone loss in osteoporosis by regulating mitochondrial function.
PEA impairs mitochondrial function in RANKL-induced BMMs, thereby repressing osteoclast differentiation via the YTHDC1/m6A-RELA/NF-κB signaling axis, which provides a novel molecular mechanism of PEA in osteoporosis treatment.
Fei Xiong, Liu-Qing Yang
· Bone · 0 citations