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Liu-Tao Ma

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Oct 2026

Juglone induces GSDME-mediated pyroptosis by targeting HSP90α ATPase domain to promote STAT3 degradation in glioblastoma multiforme.

Glioblastoma (GBM) is a highly aggressive primary brain tumor with grim overall median survival, and its therapeutic efficacy is severely limited due to drug resistance. Therefore, developing effective and safe chemotherapy regimens is urgently required. Juglone, a natural bioactive constituent derived from traditional...

Hao Wu, Shuai Chen, Jia-Wen Li et al. · 0 citations

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