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Author

Liu Yang

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Open access Sep 2026

Saikosaponin A ameliorates acute lung injury by targeting eIF3f to regulate p62 ubiquitination and mitochondrial autophagy flux.

BACKGROUND Acute lung injury (ALI) is marked by an exaggerated inflammatory response, elevated oxidative stress, and impaired mitochondrial function, while effective targeted therapeutic strategies remain scarce. Saikosaponin A (SSA), a major active component of Bupleurum, exhibits anti-inflammatory activity, yet its d...

Cheng-Hao Bi, Ya-Wei Zhao, Jin-Xia Wei et al. · 0 citations

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