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Review Sep 2026

A New Omics View of Retinal Aging: Cell-Type Vulnerability, Spatial Niches, and Disease Susceptibility.

Classical accounts of retinal aging emphasize oxidative, mitochondrial, inflammatory, vascular, proteostatic, and retinal pigment epithelium (RPE)-centered mechanisms. Omics studies now confirm and refine this non-uniformity, showing that aging-associated signals vary by cell type, anatomical niche, molecular layer, an...

Liu Yang, Zhi-Jie Li · 0 citations

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