Author

Liyan Chen

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Review Open access Jul 2026

Metabolomics in renal cystic disease: links to mechanisms and identification of pathways for potential pre-diagnosis.

This review synthesizes existing metabolomics studies of human PKD and renal cystic disease with significant metabolites extracted, and pathway enrichment analyses conducted at the levels of overall cystic kidney disease and the ADPKD/Pkd1/non-Pkd1 subsets to identify significant pathways and their associated metabolic...

Liyan Chen, David I. Broadhurst, A. Shafaei et al. · AJP - Renal Physiology · 0 citations

Review Open access Aug 2026

Associations of cardiovascular-kidney-metabolic syndrome stage with trabecular bone score and bone mineral density

A previously unrecognized dissociation in CKM syndrome was revealed, in which advanced stages were associated with a lower overall TBS despite higher FN BMD and LS BMD, which parallels the well-established diabetic bone paradox.

Jiashuang Lin, Wei-Feng Chen, Xiaoyu Hong et al. · Metabolism and Target Organ... · 0 citations