Author

Loai Aljerf

2 papers indexed here

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Open access Aug 2026

miR-451a is a differentially expressed blood-based microRNA in newly diagnosed CML identified by high-throughput profiling

microRNAs (miRNAs) are emerging as promising biomarkers in hematological malignancies due to their stability in blood. This study aimed to investigate the differential expression of miRNAs in chronic myeloid leukemia (CML) and evaluate the potential of miR-451a as a candidate whole-blood miRNA marker. We c...

Surbhi Gupta, Nitu Nigam, Abdullah H. Maad et al. · BMC Cancer · 0 citations

Aug 2026

In vivo evaluation of the dual MOP/NOP agonist AT121: a potent analgesic that delays opioid tolerance and offers a superior withdrawal suppression profile to methadone.

To evaluate the in vivo analgesic efficacy, tolerance liability, and dependence-modulating potential of AT121, a dual μ-opioid (MOP)/nociceptin (NOP) partial agonist, compared with morphine in Wistar rats. Male Wistar rats (n = 264) underwent tail-flick thermal nociception assays to assess dose-response and duration of...

Baraa E Elawy, Loai Aljerf, Shaza A Allaham et al. · Neuroscience · 0 citations