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Author

Lola Le Breton

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2 papers indexed here

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Open access Sep 2026

A biological-response compound representation allows chemical perturbation prediction across cell lines

Accurately predicting cellular responses to drugs remains a challenge with the potential to reduce experimental screening costs and accelerate drug discovery. Current computational approaches represent compounds through chemical structures, which carry little information regarding their activity within biological syste...

Léa Kaufmann, Lola Le Breton, E. Carraz-Billat et al. · 0 citations
Open access Jul 2026

pLM representations unlock metagenomic space beyond homology

Residue Embedding Diversity (RED), a metric for protein quality assessment orders of magnitude cheaper than likelihood, and a calibration task that measures model alignment with natural evolutionary distributions are introduced.

Lola Le Breton, David Heurtel-Depeiges, Douglas C. Millar et al. · 1 citation

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