Open access
Aug 2026
p38β-mediated BiP phosphorylation drives stemness and chemoresistance by suppressing UPR activation in hepatocellular carcinoma
It is discovered that p38β/MAPK11 phosphorylation of BiP promotes stemness and chemoresistance in HCC, revealing a targetable p38β–BiP axis in HCC.
Liang Xu, I. B. Huang, Minghe Zhang et al.
· Nature Communications · 0 citations