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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Lorena Fernandez-Mosquera

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Open access Sep 2026

Redox state of Protein Kinase A RIα coordinates lysosomal calcium signaling and mitochondrial homeostasis.

Protein Kinase A (PKA) Regulatory RIα cysteine redox state regulates docking to D-AKAP1 and may control Drp1 phosphorylation, a principal mediator of mitochondrial fission. RIα C17S knock-in (KI) mice, unable to form disulfides and therefore mimicking the reduced kinase, exhibited enlarged dysfunctional mitochondria. U...

Lorena Fernandez-Mosquera, Philip Eaton · 0 citations

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