Author

Lorenz Pichler

2 papers indexed here

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Open access Sep 2026

TLR-mediated activation of synovial fibroblasts from osteoarthritis patients promotes chondrocyte dysfunction

Objective Toll-like receptor (TLR) activation by cartilage-derived damage-associated molecular patterns contributes to osteoarthritis (OA) pathogenesis, but the role of synovial fibroblasts in this process remains incompletely understood. We investigated the TLR responsiveness of human OA synovial fibroblasts and deter...

Yu-Jie Dai, Ao Gong, N. Durán-Hernández et al. · bioRxiv · 0 citations

Editorial Open access Sep 2026

The right measure for the right question: A framework for domain-matched patient-reported outcome measure selection in knee arthroplasty research.

Patient-reported outcome measures (PROMs) are one of the primary tools for evaluating outcomes in knee arthroplasty research. Yet, they are frequently selected by convention rather than scientific rationale. The available instruments differ substantially in their measurement domains, spanning joint-specific symptoms an...

Lorenz Pichler, M. El Kayali, R. von Eisenhart-Rothe et al. · Knee Surgery, Sports Traumat... · 0 citations