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Lorenz Thost

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Review Open access Sep 2026

Radical SAM-dependent enzymes: Jacks-of-all-trades in RiPP pathways.

Covering: up to 2026The cofactor S-adenosyl-L-methionine (SAM) plays a key role in the biosynthesis of ribosomally synthesised and post-translationally modified peptide (RiPP) natural products. SAM-dependent enzymes have been shown to catalyse important steps in RiPP biosynthesis, including methylation, desaturation, e...

Panagiota-Hanna Koutsandrea, Lorenz Thost, Alicia Courvoisier-Clément et al. · 0 citations

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