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Lovelace J. Luquette

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Open access Sep 2026

Somatic mutations and single-nucleus transcriptomics reveal uniquely human properties of neuronal aging

Human brain aging is frequently studied in model mammals that rarely show the natural age-related neurodegenerative conditions that afflict humans, yet little is known about how genomic stability compares across species during aging. Although somatic single nucleotide variant (SNV) and short insertion/deletion (Indel)...

Emre Caglayan, Ishaan Lamba, Monica Manam Devi et al. · 0 citations

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