Author

Lu Chai

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Aug 2026

Reprogramming of lipid metabolism by PFKL promotes the adaptation of pancreatic ductal adenocarcinoma to glucose deprivation.

PFKL plays a key role in coordinating LD-mitochondria tethering under glucose deprivation in PDAC, and targeting the p38-PFKL-PLIN2-CPT1A axis may represent a promising therapeutic strategy.

Lu Chai, Zhaoyuan Meng, Zhi-Min Lu et al. · Cellular Signalling · 0 citations