Author

Lulong Bo

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Review Open access Oct 2026

Cell death in ischemia-reperfusion injury: beyond a single-cell-death perspective

Ischemia-reperfusion injury (IRI) contributes to the pathogenesis of major diseases, including acute kidney injury, stroke, and myocardial infarction. Multiple forms of cell death, including apoptosis, necroptosis, pyroptosis, autophagy, and ferroptosis, are key contributors to IRI. The interplay among these cell-death...

Chuan-Gang Yao, Qi Wu, Zhi Wang et al. · Biomarker Research · 0 citations

Open access Aug 2026

Establishing the Median Effective Dose of Tegileridine for Immediate Postoperative Analgesia Following Laparoscopic Colorectal Cancer Surgery: A Sequential Dose-Finding Study

Background: To determine the median effective dose (ED 50 ) of tegileridine for immediate postoperative analgesia following laparoscopic colorectal cancer surgery (LCRS), and to evaluate its safety profile. Methods: A modified Dixon’s up-and-down sequential method was employed, starting with an initial tegileridine dos...

Minna Guo, Tong Wang, Shuchi Lin et al. · Drug Design, Development and... · 0 citations