Author

Lu Lu

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Open access Sep 2026

Ilexoside K Ameliorates Atherosclerosis by Suppressing CD72hi Macrophages and Blocking CXCL12–CXCR4 Axis to Inhibit Endothelial Pyroptosis

ABSTRACT Atherosclerotic cardiovascular disease (ASCVD) remains the leading global cause of mortality, with substantial residual inflammatory risk persisting despite statin therapy. We identify a c‐Rel‐driven CD72hi macrophage subset markedly enriched in human and murine atherosclerotic plaques, whose abundance correla...

Xing-Ling He, Si-Jing Li, Jia-Hui Chen et al. · Advancement of science · 0 citations

Review Open access Jul 2026

The potential role of aberrant microglial synaptic pruning in the neurodevelopmental pathogenesis of tourette syndrome

A perspective of tourette syndrome is proposed as a microstructural developmental disorder of the circuitry rather than a mere neurotransmitter imbalance, providing a critical theoretical foundation for developing precise, next-generation neuroimmune-modulating interventions.

Lu Lu, Y. Zang, Caiwei Song et al. · Frontiers in Neuroscience · 0 citations