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Open access Sep 2026

FPNuNet: a frequency-aware prompt-guided network for nuclear segmentation and classification in immunohistochemistry images

On CD47-IHCNuSC, FPNuNet achieves the best instance-segmentation and aggregate subtype-classification performance among all evaluated methods under challenging IHC staining conditions and is suggested to provide a promising framework for robust biomarker-oriented computational pathology analysis.

Lu-Lu Qin, Zhi-Gang Pei, Xu-Dong He et al. · 0 citations

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