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Sep 2026

Rapid detection of Cd2+ ions in rice using DNAzyme gated graphene field-effect transistor.

Cadmium-contaminated rice poses a serious threat to public health, necessitating rapid screening methods. Unfortunately, traditional cadmium detection techniques are often cumbersome and expensive, making them unsuitable for on-site applications. In this study, we developed a graphene field-effect transistor (GFET) bio...

Jian-Peng Chen, Song-Jiao Luo, Yu Mao et al. · 1 citation
Open access Aug 2026

Specific cleavage of 5′ overhangs of non-target strand by Cas9 activated by target DNA binding

Abstract The clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 system has become a powerful genome-editing tool that uses RNA–DNA pairing to cleave target DNA with protospacer adjacent motif (PAM) sequences. While its primary function is well-studied, secondary activities remain poorly understood,...

Shaokang Lv, Qi Wang, Sheng-Jie Gao et al. · 0 citations

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